Publications

Botti V, De Bei O, Marchetti M, Campanini B, Cannistraro S, Bettati S, Bizzarri AR. Nanoscale dynamical investigation of the hemoglobin complex with the bacterial protein IsdB: is their interaction stabilized by catch bonds? Nanoscale, 2024; https://doi.org/10.1039/D3NR05241A

Cozzi M, Failla MC, Gianquinto E, Kovachka S, Buoli Comani V, Compari C, et al. Chasing new targets to fight antimicrobial resistance: identification of small molecules affecting the interaction of human hemoglobin with the IsdB hemophore of Staphylococcus aureus. ChemRxiv. 2024; doi:10.26434/chemrxiv-2024-h23vm. This content is a preprint and has not been peer-reviewed.
De Bei O, Marchetti M, Guglielmo S, Gianquinto E, Spyrakis F, Campanini B, Bettati S, Levantino M, Ronda L. Time-resolved X-ray solution scattering unveils the sequence of events leading to human Hb heme capture by Staphylococcus aureus IsdB. B

De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S. Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2116708119. doi: 10.1073/pnas.2116708119. Epub 2022 Mar 31. PMID: 35357971; PMCID: PMC9168843.